About Fibroblast growth factor-binding protein 2
Fibroblast growth factor-binding protein 2 (FGFBP2) is a protein
from Homo sapiens identified by UniProt accession
Q9BYJ0, 223 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Fibroblast growth factor-binding protein 2 |
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| UniProt accession | Q9BYJ0 |
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| Gene | FGFBP2 |
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| Organism | Homo sapiens |
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| Length | 223 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (68)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.24
- breast adenocarcinoma · score 0.23
- cutaneous melanoma · score 0.18
- head and neck squamous cell carcinoma · score 0.11
- vitamin D measurement · score 0.07
- electrocardiography · score 0.06
- diastolic blood pressure · score 0.04
- pulse pressure measurement · score 0.04
- neoplasm · score 0.04
- hepatocellular carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYJ0-F1 | alphafold | PREDICTED | 71.82 | — |
Amino-acid sequence (223 residues)
MKFVPCLLLV TLSCLGTLGQ APRQKQGSTG EEFHFQTGGR DSCTMRPSSL GQGAGEVWLR VDCRNTDQTY WCEYRGQPSM CQAFAADPKP YWNQALQELR RLHHACQGAP VLRPSVCREA GPQAHMQQVT SSLKGSPEPN QQPEAGTPSL RPKATVKLTE ATQLGKDSME ELGKAKPTTR PTAKPTQPGP RPGGNEEAKK KAWEHCWKPF QALCAFLISF FRG
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