About Sterile alpha motif domain-containing protein 10
Sterile alpha motif domain-containing protein 10 (SAMD10) is a protein
from Homo sapiens identified by UniProt accession
Q9BYL1, 202 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Sterile alpha motif domain-containing protein 10 |
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| UniProt accession | Q9BYL1 |
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| Gene | SAMD10 |
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| Organism | Homo sapiens |
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| Length | 202 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (16)
Diseases linked to this target (Open Targets).
- autosomal dominant retinitis pigmentosa · score 0.12
- lean body mass · score 0.11
- fat body mass · score 0.09
- whole body water mass · score 0.08
- insomnia measurement · score 0.07
- alkaline phosphatase measurement · score 0.05
- tonsillectomy risk measurement · score 0.05
- Varicose veins · score 0.03
- total blood protein measurement · score 0.03
- grip strength measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYL1-F1 | alphafold | PREDICTED | 67.28 | — |
Amino-acid sequence (202 residues)
MFTELRSKLS PPRGRAGAVR AGFGERRDVD ATAHFSFCRT LLEHTVSAES IPCHLPRTPG TSLTWHDSRS QRAASSRPIK LLQQPGTDTP QGRLYSDHYG LYHTSPSLGG LTRPVVLWSQ QDVCKWLKKH CPHNYLVYVE AFSQHAITGR ALLRLNAEKL QRMGLAQEAQ RQEVLQQVLR LQVREEGRSL QLLSQASFGK MS
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