Sulfiredoxin-1 (SRXN1)

About Sulfiredoxin-1

Sulfiredoxin-1 (SRXN1) is a protein from Homo sapiens identified by UniProt accession Q9BYN0, 137 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein name	Sulfiredoxin-1
UniProt accession	Q9BYN0
Gene	SRXN1
Organism	Homo sapiens
Length	137 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (96)

Diseases linked to this target (Open Targets).

high density lipoprotein cholesterol measurement · score 0.27
hepatocellular carcinoma · score 0.10
neoplasm · score 0.09
alkaline phosphatase measurement · score 0.07
triglyceride measurement · score 0.06
melanoma · score 0.06
non-small cell lung carcinoma · score 0.05
birth weight · score 0.05
esophageal squamous cell carcinoma · score 0.05
gestational diabetes · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYN0-F1	alphafold	PREDICTED	83.69	—

Amino-acid sequence (137 residues)

MGLRAGGTLG RAGAGRGAPE GPGPSGGAQG GSIHSGRIAA VHNVPLSVLI RPLPSVLDPA KVQSLVDTIR EDPDSVPPID VLWIKGAQGG DYFYSFGGCH RYAAYQQLQR ETIPAKLVQS TLSDLRVYLG ASTPDLQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards