Keratin-associated protein 4-1 (KRTAP4-1)

About Keratin-associated protein 4-1

Keratin-associated protein 4-1 (KRTAP4-1) is a protein from Homo sapiens identified by UniProt accession Q9BYQ7, 146 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Keratin-associated protein 4-1
UniProt accession	Q9BYQ7
Gene	KRTAP4-1
Organism	Homo sapiens
Length	146 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

prostate adenocarcinoma · score 0.18
head and neck squamous cell carcinoma · score 0.18
clear cell renal carcinoma · score 0.18
non-small cell lung carcinoma · score 0.04
Crohn's disease · score 0.00
atopic eczema · score 0.00
neoplasm · score 0.00
ulcerative colitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYQ7-F1	alphafold	PREDICTED	36.65	—

Amino-acid sequence (146 residues)

MVNSCCGSVC SDQGCDQGLC QETCCRPSCC QTTCCCPSCV VSSCCRPSCS QTTCCQTTCC RPSCCHPVCC QTTCRPSCGV SSCCRPLCCQ TTCHPSCGMS SCCRPLCCQT TCRPSCGVSS CCRPLCCQTT CCRATCCRPS CCGSSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards