About Keratin-associated protein 4-9
Keratin-associated protein 4-9 (KRTAP4-9) is a protein
from Homo sapiens identified by UniProt accession
Q9BYQ8, 210 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Keratin-associated protein 4-9 |
|---|
| UniProt accession | Q9BYQ8 |
|---|
| Gene | KRTAP4-9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.25
- body mass index · score 0.23
- body weight · score 0.21
- clear cell renal carcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- prostate adenocarcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- waist circumference · score 0.17
- fat body mass · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYQ8-F1 | alphafold | PREDICTED | 36.77 | — |
Amino-acid sequence (210 residues)
MVSSCCGSVC SDQGCGQDLC QETCCRPSCC ETTCCRTTCC RPSCCVSSCC RPQCCQSVCC QPTCSRPSCC QTTCCRTTCY RPSCCVSSCC RPQCCQPACC QPTCCRPSCC ETTCCHPRCC ISSCCRPSCC VSSCCKPQCC QSVCCQPNCC RPSCSISSCC RPSCCESSCC RPCCCVRPVC GRVSCHTTCY RPTCVISSCP RPLCCASSCC
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