Keratin-associated protein 4-8 (KRTAP4-8)

About Keratin-associated protein 4-8

Keratin-associated protein 4-8 (KRTAP4-8) is a protein from Homo sapiens identified by UniProt accession Q9BYQ9, 185 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Keratin-associated protein 4-8
UniProt accession	Q9BYQ9
Gene	KRTAP4-8
Organism	Homo sapiens
Length	185 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

prostate adenocarcinoma · score 0.18
head and neck squamous cell carcinoma · score 0.18
glioblastoma multiforme · score 0.18
breast adenocarcinoma · score 0.18
neuroblastoma · score 0.13
body mass index · score 0.09
waist circumference · score 0.02
neoplasm · score 0.00
atopic eczema · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYQ9-F1	alphafold	PREDICTED	34.88	—

Amino-acid sequence (185 residues)

MVNSCCGSVC SDQGCGQDLC QETCCCPSCC QTTCCRTTCY RPSYSVSCCC RPQCCQSVCC QPTCCRPSCC VSSCCKPQCC QSVCCQPTCC HPSCCISSCC RPSCCVSSCC KPQCCQSVCC QPNCCRPSCS ISSCCRPSCC ESSCCRPCCC LRPVCGRVSC HTTCYRPACV ISTCPRPVCC ASSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards