Keratin-associated protein 4-7 (KRTAP4-7)

About Keratin-associated protein 4-7

Keratin-associated protein 4-7 (KRTAP4-7) is a protein from Homo sapiens identified by UniProt accession Q9BYR0, 155 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Keratin-associated protein 4-7
UniProt accession	Q9BYR0
Gene	KRTAP4-7
Organism	Homo sapiens
Length	155 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.18
prostate adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
esophageal cancer · score 0.14
atopic eczema · score 0.00
psoriasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYR0-F1	alphafold	PREDICTED	36.76	—

Amino-acid sequence (155 residues)

MVSSCCGSVC SDQGCSQDLC QETCCRPSCC QTTCCRTTCY RPSCCVSSCC RPQCCQSVCC QPTCCRPTCC ETTCCHPRCC ISSCCRPSCC MSSCCKPQCC QSVCCQPTCC RPSCCRPCCC LRPVCGRVSC HTTCYRPTCV ISTCPRPLCC ASSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards