Keratin-associated protein 4-3 (KRTAP4-3)

About Keratin-associated protein 4-3

Keratin-associated protein 4-3 (KRTAP4-3) is a protein from Homo sapiens identified by UniProt accession Q9BYR4, 195 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 4-3
UniProt accession	Q9BYR4
Gene	KRTAP4-3
Organism	Homo sapiens
Length	195 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
atopic eczema · score 0.00
psoriasis · score 0.00
Sjogren syndrome · score 0.00
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYR4-F1	alphafold	PREDICTED	31.01	—

Amino-acid sequence (195 residues)

MVSSCCGSVC SDQSCGQGLG QESCCRPSCC QTTCCRTTCC RPSCCISSCC RPSCCISSCC KPSCCRTTCC RPSCCISSCC RPSCCISSCC KPSCCRTTCC RPSCCISSCC RPSCCISSCC KPSCCQTTCC RPSCCISSCY RPQCCQPSCC RPACCISSCC HPSCCVSSCR CPFSCPTTCC RTTCFHPICC GSSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards