Keratin-associated protein 4-2 (KRTAP4-2)

About Keratin-associated protein 4-2

Keratin-associated protein 4-2 (KRTAP4-2) is a protein from Homo sapiens identified by UniProt accession Q9BYR5, 136 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Keratin-associated protein 4-2
UniProt accession	Q9BYR5
Gene	KRTAP4-2
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
thyroid gland adenocarcinoma · score 0.16
esophageal cancer · score 0.14
gastric carcinoma · score 0.00
diabetes mellitus · score 0.00
glioblastoma multiforme · score 0.00
cancer · score 0.00
atopic eczema · score 0.00
psoriasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYR5-F1	alphafold	PREDICTED	39.23	—

Amino-acid sequence (136 residues)

MVNSCCGSVC SDQGCGLENC CRPSCCQTTC CRTTCCRPSC CVSSCCRPQC CQSVCCQPTC CSPSCCQTTC CRTTCCRPSC CVSSCFRPQC CQSVYCQPTC CRPSCGQTTC CRTTCYRPSC CVSTCCRPTC SSGSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards