Keratin-associated protein 1-5 (KRTAP1-5)

About Keratin-associated protein 1-5

Keratin-associated protein 1-5 (KRTAP1-5) is a protein from Homo sapiens identified by UniProt accession Q9BYS1, 174 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Keratin-associated protein 1-5
UniProt accession	Q9BYS1
Gene	KRTAP1-5
Organism	Homo sapiens
Length	174 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
prostate adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
sebaceous of Jadassohn nevus · score 0.05
hair color · score 0.04
colorectal adenocarcinoma · score 0.04
non-small cell lung carcinoma · score 0.03
cystic fibrosis · score 0.01
Hydrolethalus · score 0.01
Crohn's disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYS1-F1	alphafold	PREDICTED	39.63	—

Amino-acid sequence (174 residues)

MTCCQTSFCG YPSFSISGTC GSSCCQPSCC ETSCCQPRSC QTSFCGFPSF STSGTCSSSC CQPSCCETSC CQPSCCETSC CQPSCCQISS CGTGCGIGGG ISYGQEGSSG AVSTRIRWCR PDSRVEGTYL PPCCVVSCTP PSCCQLHHAQ ASCCRPSYCG QSCCRPVCCC EPTC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards