About Voltage-gated purine nucleotide uniporter SLC17A9
Voltage-gated purine nucleotide uniporter SLC17A9 (SLC17A9) is a protein
from Homo sapiens identified by UniProt accession
Q9BYT1, 436 residues long.
MolForge cross-references it against 0 known binders and
129 disease associations.
Target properties
| Protein name | Voltage-gated purine nucleotide uniporter SLC17A9 |
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| UniProt accession | Q9BYT1 |
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| Gene | SLC17A9 |
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| Organism | Homo sapiens |
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| Length | 436 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (129)
Diseases linked to this target (Open Targets).
- disseminated superficial actinic porokeratosis · score 0.55
- monocyte count · score 0.08
- hepatocellular carcinoma · score 0.08
- MODY · score 0.08
- nonpapillary renal cell carcinoma · score 0.08
- age at menopause · score 0.07
- neoplasm · score 0.06
- hyperinsulinism due to glucokinase deficiency · score 0.06
- hyperinsulinism due to INSR deficiency · score 0.06
- mean platelet volume · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYT1-F1 | alphafold | PREDICTED | 89.54 | — |
Amino-acid sequence (436 residues)
MQPPPDEARR DMAGDTQWSR PECQAWTGTL LLGTCLLYCA RSSMPICTVS MSQDFGWNKK EAGIVLSSFF WGYCLTQVVG GHLGDRIGGE KVILLSASAW GSITAVTPLL AHLSSAHLAF MTFSRILMGL LQGVYFPALT SLLSQKVRES ERAFTYSIVG AGSQFGTLLT GAVGSLLLEW YGWQSIFYFS GGLTLLWVWY VYRYLLSEKD LILALGVLAQ SRPVSRHNRV PWRRLFRKPA VWAAVVSQLS AACSFFILLS WLPTFFEETF PDAKGWIFNV VPWLVAIPAS LFSGFLSDHL INQGYRAITV RKLMQGMGLG LSSVFALCLG HTSSFCESVV FASASIGLQT FNHSGISVNI QDLAPSCAGF LFGVANTAGA LAGVVGVCLG GYLMETTGSW TCLFNLVAII SNLGLCTFLV FGQAQRVDLS STHEDL
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