About Serine/threonine-protein kinase 33
Serine/threonine-protein kinase 33 (STK33) is a protein
from Homo sapiens identified by UniProt accession
Q9BYT3, 514 residues long.
MolForge cross-references it against 0 known binders and
191 disease associations.
Target properties
| Protein name | Serine/threonine-protein kinase 33 |
|---|
| UniProt accession | Q9BYT3 |
|---|
| Gene | STK33 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 514 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (10)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (191)
Diseases linked to this target (Open Targets).
- body mass index · score 0.36
- IGF-1 measurement · score 0.29
- alcohol consumption measurement · score 0.26
- pancreatic neoplasm · score 0.26
- body height · score 0.25
- age at assessment · score 0.24
- sex interaction measurement · score 0.24
- Snoring · score 0.23
- alcohol use disorder measurement · score 0.23
- erythrocyte count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYT3-F1 | alphafold | PREDICTED | 67.16 | — |
Amino-acid sequence (514 residues)
MADSGLDKKS TKCPDCSSAS QKDVLCVCSS KTRVPPVLVV EMSQTSSIGS AESLISLERK KEKNINRDIT SRKDLPSRTS NVERKASQQQ WGRGNFTEGK VPHIRIENGA AIEEIYTFGR ILGKGSFGIV IEATDKETET KWAIKKVNKE KAGSSAVKLL EREVNILKSV KHEHIIHLEQ VFETPKKMYL VMELCEDGEL KEILDRKGHF SENETRWIIQ SLASAIAYLH NNDIVHRDLK LENIMVKSSL IDDNNEINLN IKVTDFGLAV KKQSRSEAML QATCGTPIYM APEVISAHDY SQQCDIWSIG VVMYMLLRGE PPFLASSEEK LFELIRKGEL HFENAVWNSI SDCAKSVLKQ LMKVDPAHRI TAKELLDNQW LTGNKLSSVR PTNVLEMMKE WKNNPESVEE NTTEEKNKPS TEEKLKSYQP WGNVPDANYT SDEEEEKQST AYEKQFPATS KDNFDMCSSS FTSSKLLPAE IKGEMEKTPV TPSQGTATKY PAKSGALSRT KKKL
Explore Serine/threonine-protein kinase 33 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets