Keratin-associated protein 2-1 (KRTAP2-1)

About Keratin-associated protein 2-1

Keratin-associated protein 2-1 (KRTAP2-1) is a protein from Homo sapiens identified by UniProt accession Q9BYU5, 128 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Keratin-associated protein 2-1
UniProt accession	Q9BYU5
Gene	KRTAP2-1
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
nonpapillary renal cell carcinoma · score 0.00
neoplasm · score 0.00
atopic eczema · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYU5-F1	alphafold	PREDICTED	34.37	—

Amino-acid sequence (128 residues)

MTGSCCGSTF SSLSYGGGCC QPCCCRDPCC CRPVTCQTTV CRPVTCVPRC TRPICEPCRR PVCCDPCSLQ EGCCRPITCC PSSCTAVVCR PCCWATTCCQ PVSVQSPCCR PPCGQPTPCS TTCRTSSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards