About Regenerating islet-derived protein 4
Regenerating islet-derived protein 4 (REG4) is a protein
from Homo sapiens identified by UniProt accession
Q9BYZ8, 158 residues long.
MolForge cross-references it against 0 known binders and
198 disease associations.
Target properties
| Protein name | Regenerating islet-derived protein 4 |
|---|
| UniProt accession | Q9BYZ8 |
|---|
| Gene | REG4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 158 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (198)
Diseases linked to this target (Open Targets).
- granulocyte count · score 0.30
- uric acid measurement · score 0.30
- Barrett's esophagus · score 0.09
- neoplasm · score 0.09
- Blackfan-Diamond anemia · score 0.08
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.08
- cancer · score 0.07
- Obesity · score 0.07
- gastric cancer · score 0.07
- alpha-thalassemia-myelodysplastic syndrome · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYZ8-F1 | alphafold | PREDICTED | 88.27 | — |
Amino-acid sequence (158 residues)
MASRSMRLLL LLSCLAKTGV LGDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
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