About Cytoplasmic polyadenylation element-binding protein 1
Cytoplasmic polyadenylation element-binding protein 1 (CPEB1) is a protein
from Homo sapiens identified by UniProt accession
Q9BZB8, 566 residues long.
MolForge cross-references it against 0 known binders and
226 disease associations.
Target properties
| Protein name | Cytoplasmic polyadenylation element-binding protein 1 |
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| UniProt accession | Q9BZB8 |
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| Gene | CPEB1 |
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| Organism | Homo sapiens |
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| Length | 566 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (226)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.39
- feeling "fed-up" measurement · score 0.28
- neurodegenerative disease · score 0.27
- sex hormone-binding globulin measurement · score 0.26
- body height · score 0.24
- HbA1c measurement · score 0.21
- age at first sexual intercourse measurement · score 0.20
- excessive daytime sleepiness measurement · score 0.19
- daytime rest measurement · score 0.17
- episodic memory · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BZB8-F1 | alphafold | PREDICTED | 65.16 | — |
Amino-acid sequence (566 residues)
MALSLEEEAG RIKDCWDNQE APALSTCSNA NIFRRINAIL DNSLDFSRVC TTPINRGIHD HLPDFQDSEE TVTSRMLFPT SAQESSRGLP DANDLCLGLQ SLSLTGWDRP WSTQDSDSSA QSSTHSVLSM LHNPLGNVLG KPPLSFLPLD PLGSDLVDKF PAPSVRGSRL DTRPILDSRS SSPSDSDTSG FSSGSDHLSD LISSLRISPP LPFLSLSGGG PRDPLKMGVG SRMDQEQAAL AAVTPSPTSA SKRWPGASVW PSWDLLEAPK DPFSIEREAR LHRQAAAVNE ATCTWSGQLP PRNYKNPIYS CKVFLGGVPW DITEAGLVNT FRVFGSLSVE WPGKDGKHPR CPPKGNMPKG YVYLVFELEK SVRSLLQACS HDPLSPDGLS EYYFKMSSRR MRCKEVQVIP WVLADSNFVR SPSQRLDPSR TVFVGALHGM LNAEALAAIL NDLFGGVVYA GIDTDKHKYP IGSGRVTFNN QRSYLKAVSA AFVEIKTTKF TKKVQIDPYL EDSLCHICSS QPGPFFCRDQ VCFKYFCRSC WHWRHSMEGL RHHSPLMRNQ KNRDSS
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