CUGBP Elav-like family member 4 (CELF4)

About CUGBP Elav-like family member 4

CUGBP Elav-like family member 4 (CELF4) is a protein from Homo sapiens identified by UniProt accession Q9BZC1, 486 residues long. MolForge cross-references it against 0 known binders and 218 disease associations.

Target properties

Protein name	CUGBP Elav-like family member 4
UniProt accession	Q9BZC1
Gene	CELF4
Organism	Homo sapiens
Length	486 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (218)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
neuroticism measurement · score 0.50
lean body mass · score 0.50
self reported educational attainment · score 0.49
depressive symptom measurement · score 0.48
unipolar depression · score 0.47
wellbeing measurement · score 0.46
white matter microstructure measurement · score 0.45
3-hydroxypropylmercapturic acid measurement · score 0.43
worry measurement · score 0.43

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BZC1-F1	alphafold	PREDICTED	61.47	—

Amino-acid sequence (486 residues)

MYIKMATLAN GQADNASLST NGLGSSPGSA GHMNGLSHSP GNPSTIPMKD HDAIKLFIGQ IPRNLDEKDL KPLFEEFGKI YELTVLKDRF TGMHKGCAFL TYCERESALK AQSALHEQKT LPGMNRPIQV KPADSESRGG SSCLRQPPSQ DRKLFVGMLN KQQSEDDVRR LFEAFGNIEE CTILRGPDGN SKGCAFVKYS SHAEAQAAIN ALHGSQTMPG ASSSLVVKFA DTDKERTMRR MQQMAGQMGM FNPMAIPFGA YGAYAQALMQ QQAALMASVA QGGYLNPMAA FAAAQMQQMA ALNMNGLAAA PMTPTSGGST PPGITAPAVP SIPSPIGVNG FTGLPPQANG QPAAEAVFAN GIHPYPAQSP TAADPLQQAY AGVQQYAGPA AYPAAYGQIS QAFPQPPPMI PQQQREGPEG CNLFIYHLPQ EFGDAELMQM FLPFGFVSFD NPASAQTAIQ AMNGFQIGMK RLKVQLKRPK DANRPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards