UPF0193 protein EVG1 (C22orf23)

Homo sapiens — UniProt Q9BZE7

Gene: C22orf23Homo sapiensSwissProt reviewed

About UPF0193 protein EVG1

UPF0193 protein EVG1 (C22orf23) is a protein from Homo sapiens identified by UniProt accession Q9BZE7, 217 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein nameUPF0193 protein EVG1
UniProt accessionQ9BZE7
GeneC22orf23
OrganismHomo sapiens
Length217 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (42)

Diseases linked to this target (Open Targets).

  • refractive error measurement · score 0.13
  • smoking status measurement · score 0.12
  • retinitis pigmentosa · score 0.11
  • age-related macular degeneration · score 0.09
  • X-linked retinal dysplasia · score 0.08
  • macula measurement · score 0.08
  • heel bone mineral density · score 0.07
  • Progressive cone dystrophy · score 0.07
  • smoking behavior · score 0.07
  • Familial exudative vitreoretinopathy · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BZE7-F1alphafoldPREDICTED80.32—

Amino-acid sequence (217 residues)

MASQKQMEVV TKGTGFRRRP KTITYTPGTC ELLRVMMKES KLTNIQQRHI MDIMKRGDAL PLQCSPTSSQ RVLPSKQIAS PIYLPPILAA RPHLRPANMC QANGAYSREQ FKPQATRDLE KEKQRLQNIF ATGKDMEERK RKAPPARQKA PAPELDRFEE LVKEIQERKE FLADMEALGQ GKQYRGIILA EISQKLREME DIDHRRSEEL RKGLATT

Explore UPF0193 protein EVG1 with MolForge

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Quick facts

UniProtQ9BZE7
GeneC22orf23
OrganismHomo sapiens
Length217
Binders0
Diseases42
View on UniProt