About UPF0193 protein EVG1
UPF0193 protein EVG1 (C22orf23) is a protein
from Homo sapiens identified by UniProt accession
Q9BZE7, 217 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | UPF0193 protein EVG1 |
| UniProt accession | Q9BZE7 |
| Gene | C22orf23 |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.13
- smoking status measurement · score 0.12
- retinitis pigmentosa · score 0.11
- age-related macular degeneration · score 0.09
- X-linked retinal dysplasia · score 0.08
- macula measurement · score 0.08
- heel bone mineral density · score 0.07
- Progressive cone dystrophy · score 0.07
- smoking behavior · score 0.07
- Familial exudative vitreoretinopathy · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9BZE7-F1 | alphafold | PREDICTED | 80.32 | — |
Amino-acid sequence (217 residues)
MASQKQMEVV TKGTGFRRRP KTITYTPGTC ELLRVMMKES KLTNIQQRHI MDIMKRGDAL PLQCSPTSSQ RVLPSKQIAS PIYLPPILAA RPHLRPANMC QANGAYSREQ FKPQATRDLE KEKQRLQNIF ATGKDMEERK RKAPPARQKA PAPELDRFEE LVKEIQERKE FLADMEALGQ GKQYRGIILA EISQKLREME DIDHRRSEEL RKGLATT
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