About Solute carrier family 13 member 1
Solute carrier family 13 member 1 (SLC13A1) is a protein
from Homo sapiens identified by UniProt accession
Q9BZW2, 595 residues long.
MolForge cross-references it against 0 known binders and
64 disease associations.
Target properties
| Protein name | Solute carrier family 13 member 1 |
|---|
| UniProt accession | Q9BZW2 |
|---|
| Gene | SLC13A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 595 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (64)
Diseases linked to this target (Open Targets).
- sitting height measurement · score 0.45
- neurodegenerative disease · score 0.34
- acute myeloid leukemia · score 0.11
- body height · score 0.09
- neoplasm · score 0.08
- Crohn's disease · score 0.06
- cancer · score 0.04
- Dent disease · score 0.04
- autosomal dominant epilepsy with auditory features · score 0.04
- adenine phosphoribosyltransferase deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BZW2-F1 | alphafold | PREDICTED | 82.03 | — |
Amino-acid sequence (595 residues)
MKFFSYILVY RRFLFVVFTV LVLLPLPIVL HTKEAECAYT LFVVATFWLT EALPLSVTAL LPSLMLPMFG IMPSKKVASA YFKDFHLLLI GVICLATSIE KWNLHKRIAL KMVMMVGVNP AWLTLGFMSS TAFLSMWLSN TSTAAMVMPI AEAVVQQIIN AEAEVEATQM TYFNGSTNHG LEIDESVNGH EINERKEKTK PVPGYNNDTG KISSKVELEK NSGMRTKYRT KKGHVTRKLT CLCIAYSSTI GGLTTITGTS TNLIFAEYFN TRYPDCRCLN FGSWFTFSFP AALIILLLSW IWLQWLFLGF NFKEMFKCGK TKTVQQKACA EVIKQEYQKL GPIRYQEIVT LVLFIIMALL WFSRDPGFVP GWSALFSEYP GFATDSTVAL LIGLLFFLIP AKTLTKTTPT GEIVAFDYSP LITWKEFQSF MPWDIAILVG GGFALADGCE ESGLSKWIGN KLSPLGSLPA WLIILISSLM VTSLTEVASN PATITLFLPI LSPLAEAIHV NPLYILIPST LCTSFAFLLP VANPPNAIVF SYGHLKVIDM VKAGLGVNIV GVAVVMLGIC TWIVPMFDLY TYPSWAPAMS NETMP
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