About Ropporin-1B
Ropporin-1B (ROPN1B) is a protein
from Homo sapiens identified by UniProt accession
Q9BZX4, 212 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Ropporin-1B |
|---|
| UniProt accession | Q9BZX4 |
|---|
| Gene | ROPN1B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.07
- melanoma · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- spermatogenic failure 55 · score 0.06
- spermatogenic failure 3 · score 0.06
- spermatogenic failure 7 · score 0.06
- spermatogenic failure 29 · score 0.05
- spermatogenic failure 11 · score 0.05
- spermatogenic failure 10 · score 0.05
- spermatogenic failure 49 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BZX4-F1 | alphafold | PREDICTED | 85.07 | — |
Amino-acid sequence (212 residues)
MAQTDKPTCI PPELPKMLKE FAKAAIRAQP QDLIQWGADY FEALSRGETP PVRERSERVA LCNWAELTPE LLKILHSQVA GRLIIRAEEL AQMWKVVNLP TDLFNSVMNV GRFTEEIEWL KFLALACSAL GVTITKTLKI VCEVLSCDHN GGLPRIPFST FQFLYTYIAE VDGEICASHV SRMLNYIEQE VIGPDGLITV NDFTQNPRVW LE
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