Tripartite motif-containing protein 6 (TRIM6)

About Tripartite motif-containing protein 6

Tripartite motif-containing protein 6 (TRIM6) is a protein from Homo sapiens identified by UniProt accession Q9C030, 488 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Tripartite motif-containing protein 6
UniProt accession	Q9C030
Gene	TRIM6
Organism	Homo sapiens
Length	488 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

body height · score 0.23
lung adenocarcinoma · score 0.07
metabolite measurement · score 0.02
cystatin C measurement · score 0.02
blood phosphate measurement · score 0.02
creatinine measurement · score 0.02
ovarian carcinoma · score 0.02
systemic lupus erythematosus · score 0.02
neoplasm · score 0.02
lymph node metastatic carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9C030-F1	alphafold	PREDICTED	86.14	—

Amino-acid sequence (488 residues)

MTSPVLVDIR EEVTCPICLE LLTEPLSIDC GHSFCQACIT PNGRESVIGQ EGERSCPVCQ TSYQPGNLRP NRHLANIVRR LREVVLGPGK QLKAVLCADH GEKLQLFCQE DGKVICWLCE RSQEHRGHHT FLVEEVAQEY QEKFQESLKK LKNEEQEAEK LTAFIREKKT SWKNQMEPER CRIQTEFNQL RNILDRVEQR ELKKLEQEEK KGLRIIEEAE NDLVHQTQSL RELISDLERR CQGSTMELLQ DVSDVTERSE FWTLRKPEAL PTKLRSMFRA PDLKRMLRVC RELTDVQSYW VDVTLNPHTA NLNLVLAKNR RQVRFVGAKV SGPSCLEKHY DCSVLGSQHF SSGKHYWEVD VAKKTAWILG VCSNSLGPTF SFNHFAQNHS AYSRYQPQSG YWVIGLQHNH EYRAYEDSSP SLLLSMTVPP RRVGVFLDYE AGTVSFYNVT NHGFPIYTFS KYYFPTTLCP YFNPCNCVIP MTLRRPSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards