Protein FAM117A (FAM117A)

About Protein FAM117A

Protein FAM117A (FAM117A) is a protein from Homo sapiens identified by UniProt accession Q9C073, 453 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Protein FAM117A
UniProt accession	Q9C073
Gene	FAM117A
Organism	Homo sapiens
Length	453 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.42
mean corpuscular hemoglobin · score 0.40
Red cell distribution width · score 0.39
serum albumin measurement · score 0.35
mean reticulocyte volume · score 0.30
calcium measurement · score 0.30
erythrocyte count · score 0.29
total blood protein measurement · score 0.29
neurodegenerative disease · score 0.28
alkaline phosphatase measurement · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9C073-F1	alphafold	PREDICTED	55.52	—

Amino-acid sequence (453 residues)

MAGAAAGGRG GGAWGPGRGG AGGLRRGCSP PAPAGSPRAG LQPLRATIPF QLQQPHQRRD GGGRAASVPC SVAPEKSVCR PQPLQVRRTF SLDTILSSYL LGQWPRDADG AFTCCTNDKA TQTPLSWQEL EGERASSCAH KRSASWGSTD HRKEISKLKQ QLQRTKLSRS GKEKERGSPL LGDHAVRGAL RASPPSFPSG SPVLRLSPCL HRSLEGLNQE LEEVFVKEQG EEELLRILDI PDGHRAPAPP QSGSCDHPLL LLEPGNLASS PSMSLASPQP CGLASHEEHR GAAEELASTP NDKASSPGHP AFLEDGSPSP VLAFAASPRP NHSYIFKREP PEGCEKVRVF EEATSPGPDL AFLTSCPDKN KVHFNPTGSA FCPVNLMKPL FPGMGFIFRN CPSNPGSPLP PASPRPPPRK DPEASKASPL PFEPWQRTPP SEEPVLFQSS LMV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards