INO80 complex subunit B (INO80B)

About INO80 complex subunit B

INO80 complex subunit B (INO80B) is a protein from Homo sapiens identified by UniProt accession Q9C086, 356 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	INO80 complex subunit B
UniProt accession	Q9C086
Gene	INO80B
Organism	Homo sapiens
Length	356 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
glioblastoma multiforme · score 0.18
platelet count · score 0.14
platelet crit · score 0.08
body height · score 0.08
appendicular lean mass · score 0.07
serum urea measurement · score 0.06
IGF-1 measurement · score 0.05
Stress urinary incontinence · score 0.04
Personality disorder · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9C086-F1	alphafold	PREDICTED	65.23	—

Amino-acid sequence (356 residues)

MSKLWRRGST SGAMEAPEPG EALELSLAGA HGHGVHKKKH KKHKKKHKKK HHQEEDAGPT QPSPAKPQLK LKIKLGGQVL GTKSVPTFTV IPEGPRSPSP LMVVDNEEEP MEGVPLEQYR AWLDEDSNLS PSPLRDLSGG LGGQEEEEEQ RWLDALEKGE LDDNGDLKKE INERLLTARQ RALLQKARSQ PSPMLPLPVA EGCPPPALTE EMLLKREERA RKRRLQAARR AEEHKNQTIE RLTKTAATSG RGGRGGARGE RRGGRAAAPA PMVRYCSGAQ GSTLSFPPGV PAPTAVSQRP SPSGPPPRCS VPGCPHPRRY ACSRTGQALC SLQCYRINLQ MRLGGPEGPG SPLLAT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards