About Transport and Golgi organization protein 6 homolog
Transport and Golgi organization protein 6 homolog (TANGO6) is a protein
from Homo sapiens identified by UniProt accession
Q9C0B7, 1094 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Transport and Golgi organization protein 6 homolog |
|---|
| UniProt accession | Q9C0B7 |
|---|
| Gene | TANGO6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1094 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.31
- neuroimaging measurement · score 0.29
- skin cancer · score 0.27
- non-melanoma skin carcinoma · score 0.27
- Agouti-related protein measurement · score 0.19
- high density lipoprotein cholesterol measurement · score 0.15
- myoepithelial tumor · score 0.11
- Red cell distribution width · score 0.09
- IGF-1 measurement · score 0.07
- blood protein measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9C0B7-F1 | alphafold | PREDICTED | 78.69 | — |
Amino-acid sequence (1094 residues)
MAARQAVGSG AQETCGLDRI LEALKLLLSP GGSGSSSLQV TKHDVLLATL KSNLSALEDK FLKDPQWKNL KLLRDEIADK AEWPQNSVDV TWSFTSQTLL LLLCLKETMI RLAANFNPGK PNPRTPEVAP ALSPDALSIS QQKTVQFVLQ FVVTLGICPY LMPGVGVPLR YRTEFGAVVQ DVVCFDAAPD ATRRLYTSCK ALLNVAQHTS LGSLIFCHHF GDIAAGLCQL GFCPTKRKLL TPAEEVLTEE ERTLSRGALR DMLDQVYQPL AVRELLILQG GPPQSCTDVK TQMRCRAPAW LRRLCGQLLS ERLMRPNGVQ AVVRGILEGA GAGAAGGSDA EVTAADWKKC DLIAKILASC PQQSLSPENY YRDICPQVLD LFHFQDKLTA RQFQRVATTT FITLSRERPH LAAKYLLQPV LAPLHRCLNT AELSESDMVP GTILVTEEEL SRCIEDVFKV YVVGNEPLTV LMDSLLPVLG VLFLLYCFTK QSVSHIRSLC QEILLWILGK LERKKAIASL KGFAGLDKAV PSLHSLCQFR VATQGGIMIT IKEAISDEDE DEALYQKVSS EQGRVEHLGD LLSHCQECGL AGDFFIFCLK ELTHVASENE TELKTEPFSS KSLLELEQHQ TLLVEGQERK LLVLQLMAVL CERMSEQIFT NVTQVVDFVA ATLQRACASL AHQAESTVES QTLSMSMGLV AVMLGGAVQL KSSDFAVLKQ LLPLLEKVSN TYPDPVIQEL AVDLRITIST HGAFATEAVS MAAQSTLNRK DLEGKIEEQQ QTSHERPTDV AHSHLEQQQS HETAPQTGLQ SNAPIIPQGV NEPSTTTSQK SGSVTTEQLQ EVLLSAYDPQ IPTRAAALRT LSHWIEQREA KALEMQEKLL KIFLENLEHE DTFVYLSAIQ GVALLSDVYP EKILPDLLAQ YDSSKDKHTP ETRMKVGEVL MRIVRALGDM VSKYREPLIH TFLRGVRDPD GAHRASSLAN LGELCQRLDF LLGSVVHEVT ACLIAVAKTD GEVQVRRAAI HVVVLLLRGL SQKATEVLSA VLKDLYHLLK HVVCLEPDDV AKLHAQLALE ELDDIMKNFL FPPQKLEKKI MVLP
Explore Transport and Golgi organization protein 6 homolog with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets