About CLOCK-interacting pacemaker
CLOCK-interacting pacemaker (CIPC) is a protein
from Homo sapiens identified by UniProt accession
Q9C0C6, 399 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | CLOCK-interacting pacemaker |
|---|
| UniProt accession | Q9C0C6 |
|---|
| Gene | CIPC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 399 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.25
- body mass index · score 0.23
- monocyte count · score 0.14
- smoking status measurement · score 0.13
- fat body mass · score 0.11
- uterine corpus cancer · score 0.10
- body weight · score 0.07
- lean body mass · score 0.05
- attention deficit hyperactivity disorder · score 0.05
- antisocial behaviour measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9C0C6-F1 | alphafold | PREDICTED | 58.11 | — |
Amino-acid sequence (399 residues)
MERKNPSRES PRRLSAKVGK GTEMKKVARQ LGMAAAESDK DSGFSDGSSE CLSSAEQMES EDMLSALGWS REDRPRQNSK TAKNAFPTLS PMVVMKNVLV KQGSSSSQLQ SWTVQPSFEV ISAQPQLLFL HPPVPSPVSP CHTGEKKSDS RNYLPILNSY TKIAPHPGKR GLSLGPEEKG TSGVQKKICT ERLGPSLSSS EPTKAGAVPS SPSTPAPPSA KLAEDSALQG VPSLVAGGSP QTLQPVSSSH VAKAPSLTFA SPASPVCASD STLHGLESNS PLSPLSANYS SPLWAAEHLC RSPDIFSEQR QSKHRRFQNT LVVLHKSGLL EITLKTKELI RQNQATQVEL DQLKEQTQLF IEATKSRAPQ AWAKLQASLT PGSSNTGSDL EAFSDHPAI
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