About Probable ribonuclease ZC3H12C
Probable ribonuclease ZC3H12C (ZC3H12C) is a protein
from Homo sapiens identified by UniProt accession
Q9C0D7, 883 residues long.
MolForge cross-references it against 0 known binders and
245 disease associations.
Target properties
| Protein name | Probable ribonuclease ZC3H12C |
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| UniProt accession | Q9C0D7 |
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| Gene | ZC3H12C |
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| Organism | Homo sapiens |
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| Length | 883 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (245)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.45
- psoriasis · score 0.44
- neurodegenerative disease · score 0.40
- type 2 diabetes mellitus · score 0.38
- apolipoprotein A 1 measurement · score 0.35
- mean platelet volume · score 0.33
- monocyte count · score 0.31
- psoriasis vulgaris · score 0.30
- bilirubin measurement · score 0.30
- total cholesterol measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9C0D7-F1 | alphafold | PREDICTED | 57.61 | — |
Amino-acid sequence (883 residues)
MPGGGSQEYG VLCIQEYRKN SKVESSTRNN FMGLKDHLGH DLGHLYVEST DPQLSPAVPW STVENPSMDT VNVGKDEKEA SEENASSGDS EENTNSDHES EQLGSISVEP GLITKTHRQL CRSPCLEPHI LKRNEILQDF KPEESQTTSK EAKKPPDVVR EYQTKLEFAL KLGYSEEQVQ LVLNKLGTDA LINDILGELV KLGNKSEADQ TVSTINTITR ETSSLESQRS ESPMQEIVTD DGENLRPIVI DGSNVAMSHG NKEVFSCRGI KLAVDWFLER GHKDITVFVP AWRKEQSRPD ALITDQEILR KLEKEKILVF TPSRRVQGRR VVCYDDRFIV KLAFESDGII VSNDNYRDLA NEKPEWKKFI DERLLMYSFV NDKFMPPDDP LGRHGPSLDN FLRKKPIVPE HKKQPCPYGK KCTYGHKCKY YHPERGSQPQ RSVADELRAM SRNTAAKTAN EGGLVKSNSV PCSTKADSTS DVKRGAPKRQ SDPSIRTQVY QDLEEKLPTK NKLETRSVPS LVSIPATSTA KPQSTTSLSN GLPSGVHFPP QDQRPQGQYP SMMMATKNHG TPMPYEQYPK CDSPVDIGYY SMLNAYSNLS LSGPRSPERR FSLDTDYRIS SVASDCSSEG SMSCGSSDSY VGYNDRSYVS SPDPQLEENL KCQHMHPHSR LNPQPFLQNF HDPLTRGQSY SHEEPKFHHK PPLPHLALHL PHSAVGARSS CPGDYPSPPS SAHSKAPHLG RSLVATRIDS ISDSRLYDSS PSRQRKPYSR QEGLGSWERP GYGIDAYGYR QTYSLPDNST QPCYEQFTFQ SLPEQQEPAW RIPYCGMPQD PPRYQDNREK IYINLCNIFP PDLVRIVMKR NPHMTDAQQL AAAILVEKSQ LGY
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