Centrosomal protein of 44 kDa (CEP44)

About Centrosomal protein of 44 kDa

Centrosomal protein of 44 kDa (CEP44) is a protein from Homo sapiens identified by UniProt accession Q9C0F1, 390 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Centrosomal protein of 44 kDa
UniProt accession	Q9C0F1
Gene	CEP44
Organism	Homo sapiens
Length	390 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

bilirubin measurement · score 0.35
heel bone mineral density · score 0.26
abortion · score 0.22
lower face morphology measurement · score 0.21
chin morphology measurement · score 0.20
electrocardiography · score 0.12
neurodegenerative disease · score 0.11
bone mineral content measurement · score 0.06
birth weight · score 0.06
parental genotype effect measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9C0F1-F1	alphafold	PREDICTED	67.58	—

Amino-acid sequence (390 residues)

MATGDLKRSL RNLEQVLRLL NYPEEVDCVG LIKGDPAASL PIISYSFTSY SPYVTELIME SNVELIAKND LRFIDAVYKL LRDQFNYKPI LTKKQFIQCG FAEWKIQIVC DILNCVMKKH KELSSLQKIP SQQRKKISSG KSEPPLGNEK ISAEAVGVDI SGRFMTSGKK KAVVIRHLYN EDNVDISEDT LSPITDVNEA VDVSDLNATE IKMPEVKVPE IKAEQQDVNV NPEITALQTM LAECQENLKK LTSIEKRLDC LEQKMKGKVM VDENTWTNLL SRVTLLETEM LLSKKNDEFI EFNEVSEDYA SCSDMDLLNP HRKSEVERPA SIPLSSGYST ASSDSTPRAS TVNYCGLNEI SEETTIQKME RMKKMFEETA ELLKCPNHYL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards