Interleukin-22 (IL22)

Homo sapiens — UniProt Q9GZX6

Gene: IL22Homo sapiensSwissProt reviewed

About Interleukin-22

Interleukin-22 (IL22) is a protein from Homo sapiens identified by UniProt accession Q9GZX6, 179 residues long. MolForge cross-references it against 0 known binders and 842 disease associations.

Target properties

Protein nameInterleukin-22
UniProt accessionQ9GZX6
GeneIL22
OrganismHomo sapiens
Length179 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (842)

Diseases linked to this target (Open Targets).

  • atopic eczema · score 0.44
  • vitamin D measurement · score 0.42
  • cancer · score 0.39
  • Eczematoid dermatitis · score 0.36
  • DNA methylation · score 0.30
  • dermatitis · score 0.29
  • thyroid gland adenocarcinoma · score 0.23
  • eosinophil count · score 0.14
  • psoriasis · score 0.12
  • infection · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9GZX6-F1alphafoldPREDICTED88.15—

Amino-acid sequence (179 residues)

MAALQKSVSS FLMGTLATSC LLLLALLVQG GAAAPISSHC RLDKSNFQQP YITNRTFMLA KEASLADNNT DVRLIGEKLF HGVSMSERCY LMKQVLNFTL EEVLFPQSDR FQPYMQEVVP FLARLSNRLS TCHIEGDDLH IQRNVQKLKD TVKKLGESGE IKAIGELDLL FMSLRNACI

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Quick facts

UniProtQ9GZX6
GeneIL22
OrganismHomo sapiens
Length179
Binders0
Diseases842
View on UniProt