Mitochondrial fission regulator 1-like (MTFR1L)

About Mitochondrial fission regulator 1-like

Mitochondrial fission regulator 1-like (MTFR1L) is a protein from Homo sapiens identified by UniProt accession Q9H019, 292 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Mitochondrial fission regulator 1-like
UniProt accession	Q9H019
Gene	MTFR1L
Organism	Homo sapiens
Length	292 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

hematocrit · score 0.24
red blood cell density measurement · score 0.23
erythrocyte count · score 0.22
body height · score 0.22
hemoglobin measurement · score 0.21
waist-hip ratio · score 0.15
BMI-adjusted waist-hip ratio · score 0.12
mean corpuscular hemoglobin concentration · score 0.10
bone density · score 0.10
urate measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H019-F1	alphafold	PREDICTED	63.72	—

Amino-acid sequence (292 residues)

MSGMEATVTI PIWQNKPHGA ARSVVRRIGT NLPLKPCARA SFETLPNISD LCLRDVPPVP TLADIAWIAA DEEETYARVR SDTRPLRHTW KPSPLIVMQR NASVPNLRGS EERLLALKKP ALPALSRTTE LQDELSHLRS QIAKIVAADA ASASLTPDFL SPGSSNVSSP LPCFGSSFHS TTSFVISDIT EETEVEVPEL PSVPLLCSAS PECCKPEHKA ACSSSEEDDC VSLSKASSFA DMMGILKDFH RMKQSQDLNR SLLKEEDPAV LISEVLRRKF ALKEEDISRK GN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards