About Interleukin-25
Interleukin-25 (IL25) is a protein
from Homo sapiens identified by UniProt accession
Q9H293, 177 residues long.
MolForge cross-references it against 0 known binders and
313 disease associations.
Target properties
| Protein name | Interleukin-25 |
|---|
| UniProt accession | Q9H293 |
|---|
| Gene | IL25 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (313)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.23
- neoplasm · score 0.10
- hepatocellular carcinoma · score 0.09
- cortical surface area measurement · score 0.08
- Rheumatoid arthritis · score 0.08
- triple-negative breast cancer · score 0.07
- cholangiocarcinoma · score 0.07
- influenza · score 0.07
- isolated agammaglobulinemia · score 0.07
- hyper-IgM syndrome type 2 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9H293-F1 | alphafold | PREDICTED | 79.03 | — |
Amino-acid sequence (177 residues)
MRERPRLGED SSLISLFLQV VAFLAMVMGT HTYSHWPSCC PSKGQDTSEE LLRWSTVPVP PLEPARPNRH PESCRASEDG PLNSRAISPW RYELDRDLNR LPQDLYHARC LCPHCVSLQT GSHMDPRGNS ELLYHNQTVF YRRPCHGEKG THKGYCLERR LYRVSLACVC VRPRVMG
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