About Fructosamine-3-kinase
Fructosamine-3-kinase (FN3K) is a protein
from Homo sapiens identified by UniProt accession
Q9H479, 309 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Fructosamine-3-kinase |
|---|
| UniProt accession | Q9H479 |
|---|
| Gene | FN3K |
|---|
| Organism | Homo sapiens |
|---|
| Length | 309 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- HbA1c measurement · score 0.49
- Red cell distribution width · score 0.36
- hemoglobin A1 measurement · score 0.31
- mean platelet volume · score 0.29
- platelet component distribution width · score 0.20
- body height · score 0.17
- chronic obstructive pulmonary disease · score 0.08
- platelet count · score 0.07
- cancer · score 0.05
- uridine-cytidineuria · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9H479-F1 | alphafold | PREDICTED | 94.30 | — |
Amino-acid sequence (309 residues)
MEQLLRAELR TATLRAFGGP GAGCISEGRA YDTDAGPVFV KVNRRTQARQ MFEGEVASLE ALRSTGLVRV PRPMKVIDLP GGGAAFVMEH LKMKSLSSQA SKLGEQMADL HLYNQKLREK LKEEENTVGR RGEGAEPQYV DKFGFHTVTC CGFIPQVNEW QDDWPTFFAR HRLQAQLDLI EKDYADREAR ELWSRLQVKI PDLFCGLEIV PALLHGDLWS GNVAEDDVGP IIYDPASFYG HSEFELAIAL MFGGFPRSFF TAYHRKIPKA PGFDQRLLLY QLFNYLNHWN HFGREYRSPS LGTMRRLLK
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