Dual specificity protein phosphatase 21 (DUSP21)

About Dual specificity protein phosphatase 21

Dual specificity protein phosphatase 21 (DUSP21) is a protein from Homo sapiens identified by UniProt accession Q9H596, 190 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Dual specificity protein phosphatase 21
UniProt accession	Q9H596
Gene	DUSP21
Organism	Homo sapiens
Length	190 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

colorectal adenocarcinoma · score 0.04
non-small cell lung carcinoma · score 0.03
hepatocellular carcinoma · score 0.03
facial morphology measurement · score 0.02
glioblastoma multiforme · score 0.01
cancer · score 0.01
melanoma · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H596-F1	alphafold	PREDICTED	91.40	—

Amino-acid sequence (190 residues)

MTASASSFSS SQGVQQPSIY SFSQITRSLF LSNGVAANDK LLLSSNRITA IVNASVEVVN VFFEGIQYIK VPVTDARDSR LYDFFDPIAD LIHTIDMRQG RTLLHCMAGV SRSASLCLAY LMKYHSMSLL DAHTWTKSRR PIIRPNNGFW EQLINYEFKL FNNNTVRMIN SPVGNIPDIY EKDLRMMISM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards