Jupiter microtubule associated homolog 2 (JPT2)

About Jupiter microtubule associated homolog 2

Jupiter microtubule associated homolog 2 (JPT2) is a protein from Homo sapiens identified by UniProt accession Q9H910, 190 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Jupiter microtubule associated homolog 2
UniProt accession	Q9H910
Gene	JPT2
Organism	Homo sapiens
Length	190 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

esophageal squamous cell carcinoma · score 0.07
nephrolithiasis · score 0.07
neoplasm · score 0.06
Snoring · score 0.05
mean corpuscular hemoglobin concentration · score 0.04
IGF-1 measurement · score 0.04
intraocular pressure measurement · score 0.02
snoring measurement · score 0.02
cancer · score 0.02
gonorrhea · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H910-F1	alphafold	PREDICTED	60.00	—

Amino-acid sequence (190 residues)

MFQVPDSEGG RAGSRAMKPP GGESSNLFGS PEEATPSSRP NRMASNIFGP TEEPQNIPKR TNPPGGKGSG IFDESTPVQT RQHLNPPGGK TSDIFGSPVT ATSRLAHPNK PKDHVFLCEG EEPKSDLKAA RSIPAGAEPG EKGSARKAGP AKEQEPMPTV DSHEPRLGPR PRSHNKVLNP PGGKSSISFY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards