E3 ubiquitin ligase RNF121 (RNF121)

About E3 ubiquitin ligase RNF121

E3 ubiquitin ligase RNF121 (RNF121) is a protein from Homo sapiens identified by UniProt accession Q9H920, 327 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	E3 ubiquitin ligase RNF121
UniProt accession	Q9H920
Gene	RNF121
Organism	Homo sapiens
Length	327 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H920-F1	alphafold	PREDICTED	84.44	—

Amino-acid sequence (327 residues)

MAAVVEVEVG GGAAGERELD EVDMSDLSPE EQWRVEHARM HAKHRGHEAM HAEMVLILIA TLVVAQLLLV QWKQRHPRSY NMVTLFQMWV VPLYFTVKLH WWRFLVIWIL FSAVTAFVTF RATRKPLVQT TPRLVYKWFL LIYKISYATG IVGYMAVMFT LFGLNLLFKI KPEDAMDFGI SLLFYGLYYG VLERDFAEMC ADYMASTIGF YSESGMPTKH LSDSVCAVCG QQIFVDVSEE GIIENTYRLS CNHVFHEFCI RGWCIVGKKQ TCPYCKEKVD LKRMFSNPWE RPHVMYGQLL DWLRYLVAWQ PVIIGVVQGI NYILGLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards