Zinc finger matrin-type protein 3 (ZMAT3)

About Zinc finger matrin-type protein 3

Zinc finger matrin-type protein 3 (ZMAT3) is a protein from Homo sapiens identified by UniProt accession Q9HA38, 289 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

Target properties

Protein name	Zinc finger matrin-type protein 3
UniProt accession	Q9HA38
Gene	ZMAT3
Organism	Homo sapiens
Length	289 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (80)

Diseases linked to this target (Open Targets).

platelet count · score 0.45
mean platelet volume · score 0.44
mean corpuscular volume · score 0.43
mean corpuscular hemoglobin · score 0.38
platelet component distribution width · score 0.37
platelet crit · score 0.36
erythrocyte count · score 0.31
mean corpuscular hemoglobin concentration · score 0.30
Abnormality of refraction · score 0.28
Red cell distribution width · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HA38-F1	alphafold	PREDICTED	68.99	—

Amino-acid sequence (289 residues)

MILLQHAVLP PPKQPSPSPP MSVATRSTGT LQLPPQKPFG QEASLPLAGE EELSKGGEQD CALEELCKPL YCKLCNVTLN SAQQAQAHYQ GKNHGKKLRN YYAANSCPPP ARMSNVVEPA ATPVVPVPPQ MGSFKPGGRV ILATENDYCK LCDASFSSPA VAQAHYQGKN HAKRLRLAEA QSNSFSESSE LGQRRARKEG NEFKMMPNRR NMYTVQNNSA GPYFNPRSRQ RIPRDLAMCV TPSGQFYCSM CNVGAGEEME FRQHLESKQH KSKVSEQRYR NEMENLGYV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards