About Ketosamine-3-kinase
Ketosamine-3-kinase (FN3KRP) is a protein
from Homo sapiens identified by UniProt accession
Q9HA64, 309 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Ketosamine-3-kinase |
|---|
| UniProt accession | Q9HA64 |
|---|
| Gene | FN3KRP |
|---|
| Organism | Homo sapiens |
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| Length | 309 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- HbA1c measurement · score 0.27
- neurodegenerative disease · score 0.25
- mean platelet volume · score 0.22
- hemoglobin A1 measurement · score 0.16
- body height · score 0.08
- plasma protein metabolism disease · score 0.05
- Posterior Leukoencephalopathy Syndrome · score 0.05
- platelet count · score 0.04
- metabolite measurement · score 0.04
- Red cell distribution width · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HA64-F1 | alphafold | PREDICTED | 93.99 | — |
Amino-acid sequence (309 residues)
MEELLRRELG CSSVRATGHS GGGCISQGRS YDTDQGRVFV KVNPKAEARR MFEGEMASLT AILKTNTVKV PKPIKVLDAP GGGSVLVMEH MDMRHLSSHA AKLGAQLADL HLDNKKLGEM RLKEAGTVGR GGGQEERPFV ARFGFDVVTC CGYLPQVNDW QEDWVVFYAR QRIQPQMDMV EKESGDREAL QLWSALQLKI PDLFRDLEII PALLHGDLWG GNVAEDSSGP VIFDPASFYG HSEYELAIAG MFGGFSSSFY SAYHGKIPKA PGFEKRLQLY QLFHYLNHWN HFGSGYRGSS LNIMRNLVK
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