Ceramide synthase 4 (CERS4)

About Ceramide synthase 4

Ceramide synthase 4 (CERS4) is a protein from Homo sapiens identified by UniProt accession Q9HA82, 394 residues long. MolForge cross-references it against 0 known binders and 133 disease associations.

Target properties

Protein name	Ceramide synthase 4
UniProt accession	Q9HA82
Gene	CERS4
Organism	Homo sapiens
Length	394 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HA82-F1	alphafold	PREDICTED	85.04	—

Amino-acid sequence (394 residues)

MLSSFNEWFW QDRFWLPPNV TWTELEDRDG RVYPHPQDLL AALPLALVLL AMRLAFERFI GLPLSRWLGV RDQTRRQVKP NATLEKHFLT EGHRPKEPQL SLLAAQCGLT LQQTQRWFRR RRNQDRPQLT KKFCEASWRF LFYLSSFVGG LSVLYHESWL WAPVMCWDRY PNQTLKPSLY WWYLLELGFY LSLLIRLPFD VKRKDFKEQV IHHFVAVILM TFSYSANLLR IGSLVLLLHD SSDYLLEACK MVNYMQYQQV CDALFLIFSF VFFYTRLVLF PTQILYTTYY ESISNRGPFF GYYFFNGLLM LLQLLHVFWS CLILRMLYSF MKKGQMEKDI RSDVEESDSS EEAAAAQEPL QLKNGAAGGP RPAPTDGPRS RVAGRLTNRH TTAT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards