About Solute carrier family 52, riboflavin transporter, member 2
Solute carrier family 52, riboflavin transporter, member 2 (SLC52A2) is a protein
from Homo sapiens identified by UniProt accession
Q9HAB3, 445 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Solute carrier family 52, riboflavin transporter, member 2 |
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| UniProt accession | Q9HAB3 |
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| Gene | SLC52A2 |
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| Organism | Homo sapiens |
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| Length | 445 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (62)
Diseases linked to this target (Open Targets).
- riboflavin transporter deficiency · score 0.80
- genetic disorder · score 0.52
- Brown-Vialetto-van Laere syndrome 1 · score 0.46
- hereditary sensory and autonomic neuropathy · score 0.46
- sensorineural hearing loss · score 0.44
- auditory neuropathy · score 0.40
- Optic atrophy · score 0.37
- cerebellar ataxia · score 0.37
- optic atrophy · score 0.37
- Sensorineural hearing impairment · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HAB3-F1 | alphafold | PREDICTED | 84.14 | — |
Amino-acid sequence (445 residues)
MAAPTPARPV LTHLLVALFG MGSWAAVNGI WVELPVVVKE LPEGWSLPSY VSVLVALGNL GLLVVTLWRR LAPGKDEQVP IRVVQVLGMV GTALLASLWH HVAPVAGQLH SVAFLALAFV LALACCASNV TFLPFLSHLP PRFLRSFFLG QGLSALLPCV LALVQGVGRL ECPPAPINGT PGPPLDFLER FPASTFFWAL TALLVASAAA FQGLLLLLPP PPSVPTGELG SGLQVGAPGA EEEVEESSPL QEPPSQAAGT TPGPDPKAYQ LLSARSACLL GLLAATNALT NGVLPAVQSF SCLPYGRLAY HLAVVLGSAA NPLACFLAMG VLCRSLAGLG GLSLLGVFCG GYLMALAVLS PCPPLVGTSA GVVLVVLSWV LCLGVFSYVK VAASSLLHGG GRPALLAAGV AIQVGSLLGA VAMFPPTSIY HVFHSRKDCA DPCDS
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