About Calaxin
Calaxin (CLXN) is a protein
from Homo sapiens identified by UniProt accession
Q9HAE3, 211 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Calaxin |
|---|
| UniProt accession | Q9HAE3 |
|---|
| Gene | CLXN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (49)
Diseases linked to this target (Open Targets).
- body height · score 0.30
- grip strength measurement · score 0.30
- BMI-adjusted hip circumference · score 0.29
- type 2 diabetes mellitus · score 0.28
- diabetic nephropathy · score 0.28
- lymphocyte count · score 0.25
- appendicular lean mass · score 0.22
- aspartate aminotransferase measurement · score 0.21
- heel bone mineral density · score 0.21
- lean body mass · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HAE3-F1 | alphafold | PREDICTED | 89.62 | — |
Amino-acid sequence (211 residues)
MNRKKLQKLT DTLTKNCKHF NKFEVNCLIK LFYDLVGGVE RQGLVVGLDR NAFRNILHVT FGMTDDMIMD RVFRGFDKDN DGCVNVLEWI HGLSLFLRGS LEEKMKYCFE VFDLNGDGFI SKEEMFHMLK NSLLKQPSEE DPDEGIKDLV EITLKKMDHD HDGKLSFADY ELAVREETLL LEAFGPCLPD PKSQMEFEAQ VFKDPNEFND M
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