Chromatin modification-related protein MEAF6 (MEAF6)

Homo sapiens — UniProt Q9HAF1

Gene: MEAF6Homo sapiensSwissProt reviewed

About Chromatin modification-related protein MEAF6

Chromatin modification-related protein MEAF6 (MEAF6) is a protein from Homo sapiens identified by UniProt accession Q9HAF1, 191 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein nameChromatin modification-related protein MEAF6
UniProt accessionQ9HAF1
GeneMEAF6
OrganismHomo sapiens
Length191 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (38)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.53
  • breast adenocarcinoma · score 0.26
  • body height · score 0.21
  • squamous cell lung carcinoma · score 0.18
  • gastric adenocarcinoma · score 0.18
  • erythrocyte count · score 0.16
  • forced expiratory volume · score 0.09
  • intraocular pressure measurement · score 0.09
  • unipolar depression · score 0.08
  • Alzheimer disease · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HAF1-F1alphafoldPREDICTED70.85—

Amino-acid sequence (191 residues)

MAMHNKAAPP QIPDTRRELA ELVKRKQELA ETLANLERQI YAFEGSYLED TQMYGNIIRG WDRYLTNQKN SNSKNDRRNR KFKEAERLFS KSSVTSAAAV SALAGVQDQL IEKREPGSGT ESDTSPDFHN QENEPSQEDP EDLDGSVQGV KPQKAASSTS SGSHHSSHKK RKNKNRHRID LKLNKKPRAD Y

Explore Chromatin modification-related protein MEAF6 with MolForge

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Quick facts

UniProtQ9HAF1
GeneMEAF6
OrganismHomo sapiens
Length191
Binders0
Diseases38
View on UniProt