About Chromatin modification-related protein MEAF6
Chromatin modification-related protein MEAF6 (MEAF6) is a protein
from Homo sapiens identified by UniProt accession
Q9HAF1, 191 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Chromatin modification-related protein MEAF6 |
| UniProt accession | Q9HAF1 |
| Gene | MEAF6 |
| Organism | Homo sapiens |
| Length | 191 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- breast adenocarcinoma · score 0.26
- body height · score 0.21
- squamous cell lung carcinoma · score 0.18
- gastric adenocarcinoma · score 0.18
- erythrocyte count · score 0.16
- forced expiratory volume · score 0.09
- intraocular pressure measurement · score 0.09
- unipolar depression · score 0.08
- Alzheimer disease · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9HAF1-F1 | alphafold | PREDICTED | 70.85 | — |
Amino-acid sequence (191 residues)
MAMHNKAAPP QIPDTRRELA ELVKRKQELA ETLANLERQI YAFEGSYLED TQMYGNIIRG WDRYLTNQKN SNSKNDRRNR KFKEAERLFS KSSVTSAAAV SALAGVQDQL IEKREPGSGT ESDTSPDFHN QENEPSQEDP EDLDGSVQGV KPQKAASSTS SGSHHSSHKK RKNKNRHRID LKLNKKPRAD Y
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