MYG1 exonuclease (MYG1)

About MYG1 exonuclease

MYG1 exonuclease (MYG1) is a protein from Homo sapiens identified by UniProt accession Q9HB07, 376 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	MYG1 exonuclease
UniProt accession	Q9HB07
Gene	MYG1
Organism	Homo sapiens
Length	376 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

Triple A syndrome · score 0.33
mean corpuscular volume · score 0.12
bone density · score 0.09
Vitiligo · score 0.09
lung adenocarcinoma · score 0.07
heel bone mineral density · score 0.05
autism · score 0.05
15q11q13 microduplication syndrome · score 0.04
alkaline phosphatase measurement · score 0.04
mean corpuscular hemoglobin concentration · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HB07-F1	alphafold	PREDICTED	89.90	—

Amino-acid sequence (376 residues)

MGHRFLRGLL TLLLPPPPLY TRHRMLGPES VPPPKRSRSK LMAPPRIGTH NGTFHCDEAL ACALLRLLPE YRDAEIVRTR DPEKLASCDI VVDVGGEYDP RRHRYDHHQR SFTETMSSLS PGKPWQTKLS SAGLIYLHFG HKLLAQLLGT SEEDSMVGTL YDKMYENFVE EVDAVDNGIS QWAEGEPRYA LTTTLSARVA RLNPTWNHPD QDTEAGFKRA MDLVQEEFLQ RLDFYQHSWL PARALVEEAL AQRFQVDPSG EIVELAKGAC PWKEHLYHLE SGLSPPVAIF FVIYTDQAGQ WRIQCVPKEP HSFQSRLPLP EPWRGLRDEA LDQVSGIPGC IFVHASGFIG GHRTREGALS MARATLAQRS YLPQIS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards