About Homeobox protein SEBOX
Homeobox protein SEBOX (SEBOX) is a protein
from Homo sapiens identified by UniProt accession
Q9HB31, 190 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Homeobox protein SEBOX |
|---|
| UniProt accession | Q9HB31 |
|---|
| Gene | SEBOX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 190 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- low density lipoprotein cholesterol measurement · score 0.13
- blood protein measurement · score 0.11
- triglyceride measurement · score 0.10
- age-related macular degeneration · score 0.09
- wet macular degeneration · score 0.09
- atrophic macular degeneration · score 0.09
- pulse pressure measurement · score 0.09
- total cholesterol measurement · score 0.08
- systolic blood pressure · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HB31-F1 | alphafold | PREDICTED | 65.21 | — |
Amino-acid sequence (190 residues)
MPSPVDASSA DGGSGLGSHR RKRTTFSKGQ LLELERAFAA WPYPNISTHE HLAWVTCLPE AKVQVWFQKR WAKIIKNRKS GILSPGSECP QSSCSLPDTL QQPWDPQMPG QPPPSSGTPQ RTSVCRHSSC PAPGLSPRQG WEGAKAVAPW GSAGASEVHP SLERATPQTS LGSLSDLIYA LAIVVNVDHS
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