Retinoid-inducible serine carboxypeptidase (SCPEP1)

About Retinoid-inducible serine carboxypeptidase

Retinoid-inducible serine carboxypeptidase (SCPEP1) is a protein from Homo sapiens identified by UniProt accession Q9HB40, 452 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Retinoid-inducible serine carboxypeptidase
UniProt accession	Q9HB40
Gene	SCPEP1
Organism	Homo sapiens
Length	452 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.29
joint disease · score 0.25
leukocyte count · score 0.24
mean platelet volume · score 0.18
myeloid white cell count · score 0.15
lymphocyte count · score 0.11
snoring measurement · score 0.06
hemoglobin measurement · score 0.03
Sepsis · score 0.03
chronic lymphocytic leukemia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HB40-F1	alphafold	PREDICTED	90.11	—

Amino-acid sequence (452 residues)

MELALRRSPV PRWLLLLPLL LGLNAGAVID WPTEEGKEVW DYVTVRKDAY MFWWLYYATN SCKNFSELPL VMWLQGGPGG SSTGFGNFEE IGPLDSDLKP RKTTWLQAAS LLFVDNPVGT GFSYVNGSGA YAKDLAMVAS DMMVLLKTFF SCHKEFQTVP FYIFSESYGG KMAAGIGLEL YKAIQRGTIK CNFAGVALGD SWISPVDSVL SWGPYLYSMS LLEDKGLAEV SKVAEQVLNA VNKGLYREAT ELWGKAEMII EQNTDGVNFY NILTKSTPTS TMESSLEFTQ SHLVCLCQRH VRHLQRDALS QLMNGPIRKK LKIIPEDQSW GGQATNVFVN MEEDFMKPVI SIVDELLEAG INVTVYNGQL DLIVDTMGQE AWVRKLKWPE LPKFSQLKWK ALYSDPKSLE TSAFVKSYKN LAFYWILKAG HMVPSDQGDM ALKMMRLVTQ QE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards