About Calcyclin-binding protein
Calcyclin-binding protein (CACYBP) is a protein
from Homo sapiens identified by UniProt accession
Q9HB71, 228 residues long.
MolForge cross-references it against 0 known binders and
98 disease associations.
Target properties
| Protein name | Calcyclin-binding protein |
|---|
| UniProt accession | Q9HB71 |
|---|
| Gene | CACYBP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (98)
Diseases linked to this target (Open Targets).
- body mass index · score 0.19
- neutrophil count · score 0.15
- keratoconus · score 0.14
- myeloid white cell count · score 0.11
- hepatocellular carcinoma · score 0.09
- body height · score 0.09
- renal cell carcinoma · score 0.08
- breast cancer · score 0.08
- urinary bladder carcinoma · score 0.08
- osteosarcoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HB71-F1 | alphafold | PREDICTED | 81.60 | — |
Amino-acid sequence (228 residues)
MASEELQKDL EEVKVLLEKA TRKRVRDALT AEKSKIETEI KNKMQQKSQK KAELLDNEKP AAVVAPITTG YTVKISNYGW DQSDKFVKIY ITLTGVHQVP TENVQVHFTE RSFDLLVKNL NGKSYSMIVN NLLKPISVEG SSKKVKTDTV LILCRKKVEN TRWDYLTQVE KECKEKEKPS YDTETDPSEG LMNVLKKIYE DGDDDMKRTI NKAWVESREK QAKGDTEF
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