About Placenta-specific protein 1
Placenta-specific protein 1 (PLAC1) is a protein
from Homo sapiens identified by UniProt accession
Q9HBJ0, 212 residues long.
MolForge cross-references it against 0 known binders and
92 disease associations.
Target properties
| Protein name | Placenta-specific protein 1 |
|---|
| UniProt accession | Q9HBJ0 |
|---|
| Gene | PLAC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (92)
Diseases linked to this target (Open Targets).
- kidney cancer · score 0.39
- neurodegenerative disease · score 0.24
- neoplasm · score 0.09
- non-small cell lung carcinoma · score 0.09
- preeclampsia · score 0.08
- breast cancer · score 0.08
- calf circumference measurement · score 0.07
- head and neck squamous cell carcinoma · score 0.07
- cancer · score 0.05
- acute lymphoblastic leukemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HBJ0-F1 | alphafold | PREDICTED | 70.24 | — |
Amino-acid sequence (212 residues)
MKVFKFIGLM ILLTSAFSAG SGQSPMTVLC SIDWFMVTVH PFMLNNDVCV HFHELHLGLG CPPNHVQPHA YQFTYRVTEC GIRAKAVSQD MVIYSTEIHY SSKGTPSKFV IPVSCAAPQK SPWLTKPCSM RVASKSRATA QKDEKCYEVF SLSQSSQRPN CDCPPCVFSE EEHTQVPCHQ AGAQEAQPLQ PSHFLDISED WSLHTDDMIG SM
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