About Collectrin
Collectrin (CLTRN) is a protein
from Homo sapiens identified by UniProt accession
Q9HBJ8, 222 residues long.
MolForge cross-references it against 0 known binders and
167 disease associations.
Target properties
| Protein name | Collectrin |
|---|
| UniProt accession | Q9HBJ8 |
|---|
| Gene | CLTRN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (167)
Diseases linked to this target (Open Targets).
- Hartnup disease · score 0.37
- acute kidney failure · score 0.09
- nephrotic syndrome · score 0.07
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.07
- focal segmental glomerulosclerosis · score 0.06
- nephronophthisis · score 0.05
- hyperprolinemia type 1 · score 0.05
- cystinuria · score 0.05
- nail-patella-like renal disease · score 0.05
- Dent disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HBJ8-F1 | alphafold | PREDICTED | 76.95 | — |
Amino-acid sequence (222 residues)
MLWLLFFLVT AIHAELCQPG AENAFKVRLS IRTALGDKAY AWDTNEEYLF KAMVAFSMRK VPNREATEIS HVLLCNVTQR VSFWFVVTDP SKNHTLPAVE VQSAIRMNKN RINNAFFLND QTLEFLKIPS TLAPPMDPSV PIWIIIFGVI FCIIIVAIAL LILSGIWQRR RKNKEPSEVD DAEDKCENMI TIENGIPSDP LDMKGGHIND AFMTEDERLT PL
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