Mitochondrial thiamine pyrophosphate carrier (SLC25A19)

About Mitochondrial thiamine pyrophosphate carrier

Mitochondrial thiamine pyrophosphate carrier (SLC25A19) is a protein from Homo sapiens identified by UniProt accession Q9HC21, 320 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

Target properties

Protein name	Mitochondrial thiamine pyrophosphate carrier
UniProt accession	Q9HC21
Gene	SLC25A19
Organism	Homo sapiens
Length	320 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HC21-F1	alphafold	PREDICTED	85.26	—

Amino-acid sequence (320 residues)

MVGYDPKPDG RNNTKFQVAV AGSVSGLVTR ALISPFDVIK IRFQLQHERL SRSDPSAKYH GILQASRQIL QEEGPTAFWK GHVPAQILSI GYGAVQFLSF EMLTELVHRG SVYDAREFSV HFVCGGLAAC MATLTVHPVD VLRTRFAAQG EPKVYNTLRH AVGTMYRSEG PQVFYKGLAP TLIAIFPYAG LQFSCYSSLK HLYKWAIPAE GKKNENLQNL LCGSGAGVIS KTLTYPLDLF KKRLQVGGFE HARAAFGQVR RYKGLMDCAK QVLQKEGALG FFKGLSPSLL KAALSTGFMF FSYEFFCNVF HCMNRTASQR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards