About Prokineticin-2
Prokineticin-2 (PROK2) is a protein
from Homo sapiens identified by UniProt accession
Q9HC23, 129 residues long.
MolForge cross-references it against 0 known binders and
201 disease associations.
Target properties
| Protein name | Prokineticin-2 |
|---|
| UniProt accession | Q9HC23 |
|---|
| Gene | PROK2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 129 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (201)
Diseases linked to this target (Open Targets).
- hypogonadotropic hypogonadism · score 0.68
- blood protein measurement · score 0.38
- Kallmann syndrome · score 0.38
- monocyte percentage of leukocytes · score 0.37
- male infertility with azoospermia or oligozoospermia due to single gene mutation · score 0.34
- Male infertility with spermatogenesis disorder · score 0.33
- monocyte count · score 0.32
- breast adenocarcinoma · score 0.25
- serum metabolite measurement · score 0.24
- eosinophil count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HC23-F1 | alphafold | PREDICTED | 70.12 | — |
Amino-acid sequence (129 residues)
MRSLCCAPLL LLLLLPPLLL TPRAGDAAVI TGACDKDSQC GGGMCCAVSI WVKSIRICTP MGKLGDSCHP LTRKNNFGNG RQERRKRKRS KRKKEVPFFG RRMHHTCPCL PGLACLRTSF NRFICLAQK
Explore Prokineticin-2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets