Glyoxalase domain-containing protein 4 (GLOD4)

About Glyoxalase domain-containing protein 4

Glyoxalase domain-containing protein 4 (GLOD4) is a protein from Homo sapiens identified by UniProt accession Q9HC38, 313 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Glyoxalase domain-containing protein 4
UniProt accession	Q9HC38
Gene	GLOD4
Organism	Homo sapiens
Length	313 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HC38-F1	alphafold	PREDICTED	89.42	—

Amino-acid sequence (313 residues)

MAARRALHFV FKVGNRFQTA RFYRDVLGMK VESCSVARLE CSGAISAHCS DYTRITEDSF SKPYDGKWSK TMVGFGPEDD HFVAELTYNY GVGDYKLGND FMGITLASSQ AVSNARKLEW PLTEVAEGVF ETEAPGGYKF YLQNRSLPQS DPVLKVTLAV SDLQKSLNYW CNLLGMKIYE KDEEKQRALL GYADNQCKLE LQGVKGGVDH AAAFGRIAFS CPQKELPDLE DLMKRENQKI LTPLVSLDTP GKATVQVVIL ADPDGHEICF VGDEAFRELS KMDPEGSKLL DDAMAADKSD EWFAKHNKPK ASG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards