WAP four-disulfide core domain protein 1 (WFDC1)

About WAP four-disulfide core domain protein 1

WAP four-disulfide core domain protein 1 (WFDC1) is a protein from Homo sapiens identified by UniProt accession Q9HC57, 220 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein name	WAP four-disulfide core domain protein 1
UniProt accession	Q9HC57
Gene	WFDC1
Organism	Homo sapiens
Length	220 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HC57-F1	alphafold	PREDICTED	68.39	—

Amino-acid sequence (220 residues)

MPLTGVGPGS CRRQIIRALC LLLLLLHAGS AKNIWKRALP ARLAEKSRAE EAGAPGGPRQ PRADRCPPPP RTLPPGACQA ARCQADSECP RHRRCCYNGC AYACLEAVPP PPVLDWLVQP KPRWLGGNGW LLDGPEEVLQ AEACSTTEDG AEPLLCPSGY ECHILSPGDV AEGIPNRGQC VKQRRQADGR ILRHKLYKEY PEGDSKNVAE PGRGQQKHFQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards