About Band 4.1-like protein 5
Band 4.1-like protein 5 (EPB41L5) is a protein
from Homo sapiens identified by UniProt accession
Q9HCM4, 733 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Band 4.1-like protein 5 |
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| UniProt accession | Q9HCM4 |
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| Gene | EPB41L5 |
|---|
| Organism | Homo sapiens |
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| Length | 733 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (74)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.43
- erythrocyte count · score 0.43
- cystatin C measurement · score 0.43
- neurodegenerative disease · score 0.42
- hematocrit · score 0.41
- red blood cell density measurement · score 0.39
- creatinine measurement · score 0.37
- serum urea measurement · score 0.37
- glomerular filtration rate · score 0.36
- urate measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HCM4-F1 | alphafold | PREDICTED | 63.55 | — |
Amino-acid sequence (733 residues)
MLSFFRRTLG RRSMRKHAEK ERLREAQRAA THIPAAGDSK SIITCRVSLL DGTDVSVDLP KKAKGQELFD QIMYHLDLIE SDYFGLRFMD SAQVAHWLDG TKSIKKQVKI GSPYCLHLRV KFYSSEPNNL REELTRYLFV LQLKQDILSG KLDCPFDTAV QLAAYNLQAE LGDYDLAEHS PELVSEFRFV PIQTEEMELA IFEKWKEYRG QTPAQAETNY LNKAKWLEMY GVDMHVVKAR DGNDYSLGLT PTGVLVFEGD TKIGLFFWPK ITRLDFKKNK LTLVVVEDDD QGKEQEHTFV FRLDHPKACK HLWKCAVEHH AFFRLRGPVQ KSSHRSGFIR LGSRFRYSGK TEYQTTKTNK ARRSTSFERR PSKRYSRRTL QMKACATKPE ELSVHNNVST QSNGSQQAWG MRSALPVSPS ISSAPVPVEI ENLPQSPGTD QHDRKCIPLN IDLLNSPDLL EATIGDVIGA SDTMETSQAL NDVNVATRLP GLGEPEVEYE TLKDTSEKLK QLEMENSPLL SPRSNIDVNI NSQEEVVKLT EKCLNNVIES PGLNVMRVPP DFKSNILKAQ VEAVHKVTKE DSLLSHKNAN VQDAATNSAV LNENNVPLPK ESLETLMLIT PADSGSVLKE ATDELDALLA SLTENLIDHT VAPQVSSTSM ITPRWIVPQS GAMSNGLAGC EMLLTGKEGH GNKDGISLIS PPAPFLVDAV TSSGPILAEE AVLKQKCLLT TEL
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